Search Results

Overview

Uniprot IDF1SRN6
Protein NameNeurolysin, mitochondrial
Gene NameNLN
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
241 HYFPVMKKCCIPETR
328 REFILNLKKKECEEK

Function

Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. Acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1

Protein Sequence

10 MVGGSGILLR 20 MTLGREAMSP 30 LQAMSSYTVD 40 GRNVLRWDLS 50 PEQIKRRTEE 60 LIAQTKQVYD 70 DIGMLDIEEV 80 TYENCLQALA 90 DVEVKYIVER 100 TMLDFPQHVS 110 SDKEVRAAST 120 EADKRLSRFD 130 IEMSMREDIF 140 LRIVRLKETC 150 DLGKIKPEAR 160 RYLEKSVKMG 170 KRNGLHLPEQ 180 VQNEIKAMKK 190 RMSELCIDFN 200 KNLNEDDTFL 210 VFSKAELGAL 220 PDDFIDSLEK 230 TDDNKYKITL 240 KYPHYFPVMK 250 KCCIPETRRK 260 MEMAFNTRCK 270 EENTIILQEL 280 LPLRAKVAKL 290 LGYSTHADFV 300 LEMNTAKSTH 310 HVTAFLDDLS 320 QKLKPLGEAE 330 REFILNLKKK 340 ECEEKGFEYD 350 GKINAWDLHY 360 YMTQTEELKY 370 SVDQEILKEY 380 FPIEVVTEGL 390 LNIYQELLGL 400 SFEQVTDAHV 410 WNKSVTLYTV 420 KDKATGEVLG 430 QFYLDLYPRE 440 GKYNHAACFG 450 LQPGCLLPDG 460 SRMMSVAALV 470 VNFSQPRAGR 480 PSLLRHDEVR 490 TYFHEFGHVM 500 HQICAQTDFA 510 RFSGTNVETD 520 FVEVPSQMLE 530 NWVWDTDSLR 540 RLSKHYKDGS 550 PITDDLLEKL 560 VASRLVNTGL 570 LTLRQIVLSK 580 VDQSLHTNTS 590 LDAASEYAKY 600 CTEILGVAAT 610 PGTNMPATFG 620 HLAGGYDGQY 630 YGYLWSEVFS 640 MDMFYSCFKK 650 EGIMNPEVGM 660 KYRNLILKPG 670 GSLDGMDMLQ 680 NFLKREPNQK 690 AFLMSRGLHA P

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005739 mitochondrion
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0004222 metalloendopeptidase activity
Biological Process GO:0006508 proteolysis

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.