Search Results
Overview
| Uniprot ID | F1SRU2 |
|---|---|
| Protein Name | Zyxin |
| Gene Name | ZYX |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 163 | MTKNDPFKARVSSGY |
| 22 | PVFYAPQKKFGPVVA |
| 23 | VFYAPQKKFGPVVAP |
| 268 | KFSPVTPKFTPVASK |
| 275 | KFTPVASKFSPGAPG |
| 291 | PGSQPSRKSGPPEAP |
| 31 | FGPVVAPKPKVNPFR |
| 324 | EKPQVQEKQHPVPPP |
| 33 | PVVAPKPKVNPFRPG |
| 529 | LDKNFHMKCYKCEVG |
Function
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression
Protein Sequence
10
MAAPRPPRAI
20
SVSAPVFYAP
30
QKKFGPVVAP
40
KPKVNPFRPG
50
DGEPPAAAGA
60
QRAQMGRVGE
70
IPPPPPEDFP
80
LPPPPVLGEA
90
DEAEGALGGA
100
FPPPPPPIEE
110
PFPPAPLEEE
120
IFPSPPPPLV
130
EEGGPEVPIQ
140
LPPQPRDKVS
150
SIDLEIDSLS
160
SLLDDMTKND
170
PFKARVSSGY
180
VPPPVSTPFI
190
SKSNTKPAPG
200
GTAPLPPWKS
210
ASSSQPLSQA
220
QPQSQTHFHV
230
QPQPQAKPQV
240
QLHVQPQAQP
250
QPVPSANTQP
260
RGPPAPSPAP
270
KFSPVTPKFT
280
PVASKFSPGA
290
PGGPGSQPSR
300
KSGPPEAPST
310
GTGSAQPPSF
320
TYAQQREKPQ
330
VQEKQHPVPP
340
PAPNQNQVRS
350
SGAPGPLTLK
360
EVEELEQLTQ
370
QLMQDMEHPQ
380
RQNVAVNEFC
390
GRCRQPLARA
400
QPAVRALGQL
410
FHITCFTCHQ
420
CEQQLQGQQF
430
YSLEGAPYCE
440
GCYTDTLEKC
450
NTCGQPITDR
460
MLRATGKAYH
470
PQCFTCVVCA
480
CPLEGTSFIV
490
DQANRPHCVP
500
DYHKQYAPRC
510
SVCAEPIMPE
520
PGREETVRVV
530
ALDKNFHMKC
540
YKCEVGHPSG
550
PGMGGGGMLL
560
TDQVVAVASL
570
EDTTATVLRV
580
HSGSTHARLG
QVLLSLGA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0045335 | phagocytic vesicle |
| Cellular Component | GO:0001725 | stress fiber |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0007160 | cell-matrix adhesion |
| Biological Process | GO:0007229 | integrin-mediated signaling pathway |
| Biological Process | GO:0043149 | stress fiber assembly |
| Biological Process | GO:0007179 | transforming growth factor beta receptor signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.