Search Results
Overview
| Uniprot ID | F1SS26 |
|---|---|
| Protein Name | Thrombospondin-1 |
| Gene Name | THBS1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 1103 | DPRHIGWKDFTAYRW |
| 1117 | WRLSHRPKTGFIRVV |
| 1129 | RVVMYEGKKIMADSG |
| 1130 | VVMYEGKKIMADSGP |
| 201 | IANLRIAKGGVNDNF |
| 262 | RTNYIGHKTKDLQAI |
| 306 | RKVTEENKELASELR |
| 349 | QNSVTICKKVSCPIM |
| 430 | CHIQECDKRFKQDGG |
| 482 | EGEARETKACQRDAC |
| 50 | GSGRRLVKGPDPSSP |
| 609 | HNGEHRCKNTDPGYN |
| 641 | VEYATANKQVCKPRN |
| 659 | DGTHDCNKNAKCNYL |
| 715 | NATYHCKKDNCPNLP |
| 919 | LVPNPDQKDSDGDGR |
Function
No function data available.
Protein Sequence
10
MGLAWGLSVL
20
FLLHVCGSNR
30
IPESGGDNSV
40
FDIFELTGAA
50
RKGSGRRLVK
60
GPDPSSPAFR
70
IEDANLIPPV
80
PDDKFQDLVD
90
AVRAEKGFLL
100
LASLRQMKKT
110
RGTLLAVERK
120
DHSGQVFSVV
130
SNGKAGTLDL
140
SLTVQGKQQV
150
VSVEEALLAT
160
GQWKSITLFV
170
QEDRAQLYID
180
CEKMENAELD
190
VPIQSIFTRD
200
LASIANLRIA
210
KGGVNDNFQG
220
VLQNVRFVFG
230
TTPEDILRNK
240
GCSSSTNVLL
250
TLDNNVVNGS
260
SPAIRTNYIG
270
HKTKDLQAIC
280
GISCDELSSM
290
VLELRGLRTI
300
VTTLQDSIRK
310
VTEENKELAS
320
ELRRPPLCYH
330
NGVQYRNNEE
340
WTVDSCTECR
350
CQNSVTICKK
360
VSCPIMPCSN
370
ATVPDGECCP
380
RCWPSDSADD
390
GWSPWSEWTS
400
CSVTCGNGIQ
410
QRGRSCDSLN
420
NRCEGSSVQT
430
RTCHIQECDK
440
RFKQDGGWSH
450
WSPWSSCSVT
460
CGDGVITRIR
470
LCNSPSPQMN
480
GKPCEGEARE
490
TKACQRDACP
500
INGGWGPWSP
510
WDICSVTCGG
520
GVQRRSRLCN
530
NPAPQFGGKD
540
CVGDETENQI
550
CNKQDCPIDG
560
CLSNPCFAGA
570
KCTSYPDGSW
580
KCGACPPGYS
590
GNGIQCEDVD
600
ECKEVPDACF
610
NHNGEHRCKN
620
TDPGYNCLPC
630
PPRFTGSQPF
640
GRSVEYATAN
650
KQVCKPRNPC
660
TDGTHDCNKN
670
AKCNYLGHYS
680
DPMYRCECKP
690
GYAGNGIICG
700
EDTDLDGWPN
710
EDLVCVANAT
720
YHCKKDNCPN
730
LPNSGQEDYD
740
KDGIGDACDD
750
DDDNDKIPDD
760
RDNCPFHYNP
770
AQYDYDRDDV
780
GDRCDNCPYN
790
HNPDQADTDN
800
NGEGDACAAD
810
IDGDGILNER
820
DNCQYVYNVD
830
QRDTDMDGVG
840
DQCDNCPLEH
850
NPDQLDSDSD
860
RIGDTCDNNQ
870
DIDEDGHQNN
880
LDNCPYVPNA
890
NQADHDKDGK
900
GDACDHDDDN
910
DGIPDDRDNC
920
RLVPNPDQKD
930
SDGDGRGDAC
940
KDDFDHDNVP
950
DIDDICPENV
960
DISETDFRRF
970
QMIPLDPKGT
980
SQNDPNWVVR
990
HQGKELVQTV
1000
NCDPGLAVGY
1010
DEFNAVDFSG
1020
TFFINTERDD
1030
DYAGFVFGYQ
1040
SSSRFYVVMW
1050
KQVTQSYWDT
1060
NPTRAQGYSG
1070
LSVKVVNSTT
1080
GPGEHLRNAL
1090
WHTGNTPGQV
1100
RTLWHDPRHI
1110
GWKDFTAYRW
1120
RLSHRPKTGF
1130
IRVVMYEGKK
1140
IMADSGPIYD
1150
KTYAGGRLGL
1160
FVFSQEMVFF
1170
SDLKYECRDS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009897 | external side of plasma membrane |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005577 | fibrinogen complex |
| Cellular Component | GO:0031091 | platelet alpha granule |
| Cellular Component | GO:0016529 | sarcoplasmic reticulum |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0070052 | collagen V binding |
| Molecular Function | GO:0004866 | endopeptidase inhibitor activity |
| Molecular Function | GO:0070051 | fibrinogen binding |
| Molecular Function | GO:0017134 | fibroblast growth factor binding |
| Molecular Function | GO:0001968 | fibronectin binding |
| Molecular Function | GO:0008201 | heparin binding |
| Molecular Function | GO:0005178 | integrin binding |
| Molecular Function | GO:0043236 | laminin binding |
| Molecular Function | GO:0030169 | low-density lipoprotein particle binding |
| Molecular Function | GO:0001786 | phosphatidylserine binding |
| Molecular Function | GO:0002020 | protease binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0072378 | blood coagulation, fibrin clot formation |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0002544 | chronic inflammatory response |
| Biological Process | GO:0043652 | engulfment of apoptotic cell |
| Biological Process | GO:0006955 | immune response |
| Biological Process | GO:0016525 | negative regulation of angiogenesis |
| Biological Process | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis |
| Biological Process | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis |
| Biological Process | GO:0001953 | negative regulation of cell-matrix adhesion |
| Biological Process | GO:0002605 | negative regulation of dendritic cell antigen processing and presentation |
| Biological Process | GO:0051918 | negative regulation of fibrinolysis |
| Biological Process | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway |
| Biological Process | GO:0032693 | negative regulation of interleukin-10 production |
| Biological Process | GO:0032695 | negative regulation of interleukin-12 production |
| Biological Process | GO:0010748 | negative regulation of long-chain fatty acid import across plasma membrane |
| Biological Process | GO:0141151 | negative regulation of nitric oxide-cGMP mediated signal transduction |
| Biological Process | GO:0010757 | negative regulation of plasminogen activation |
| Biological Process | GO:0010754 | negative regulation of receptor guanylyl cyclase signaling pathway |
| Biological Process | GO:1903671 | negative regulation of sprouting angiogenesis |
| Biological Process | GO:0032720 | negative regulation of tumor necrosis factor production |
| Biological Process | GO:0045766 | positive regulation of angiogenesis |
| Biological Process | GO:0043536 | positive regulation of blood vessel endothelial cell migration |
| Biological Process | GO:0050921 | positive regulation of chemotaxis |
| Biological Process | GO:2000353 | positive regulation of endothelial cell apoptotic process |
| Biological Process | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| Biological Process | GO:0010763 | positive regulation of fibroblast migration |
| Biological Process | GO:0043032 | positive regulation of macrophage activation |
| Biological Process | GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0042327 | positive regulation of phosphorylation |
| Biological Process | GO:2000379 | positive regulation of reactive oxygen species metabolic process |
| Biological Process | GO:0048661 | positive regulation of smooth muscle cell proliferation |
| Biological Process | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process | GO:0045727 | positive regulation of translation |
| Biological Process | GO:0032760 | positive regulation of tumor necrosis factor production |
| Biological Process | GO:0051592 | response to calcium ion |
| Biological Process | GO:0009749 | response to glucose |
| Biological Process | GO:0032026 | response to magnesium ion |
| Biological Process | GO:0006986 | response to unfolded protein |
| Biological Process | GO:0009410 | response to xenobiotic stimulus |
| Biological Process | GO:0002040 | sprouting angiogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.