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Overview

Uniprot IDF1STE6
Protein NameThioredoxin domain-containing protein 9
Gene NameTXNDC9
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
125 HLETKFLKLNVEKAP
130 FLKLNVEKAPFLCER
208 KFGTNFTKLEKKTIR

Function

Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin

Protein Sequence

10 MEANASVDMF 20 SKVLENQLLQ 30 TTKLVEEHLD 40 SEIQKLDQMD 50 EDELERLKEK 60 RLEALRKAQQ 70 QKQEWLSKGH 80 GEYREIPSER 90 DFFQEVKESK 100 KVVCHFYRDS 110 TFRCKILDRH 120 LAILSKKHLE 130 TKFLKLNVEK 140 APFLCERLRI 150 KVIPTLALVK 160 DGKTQDFVVG 170 FSDLGNTDDF 180 TTETLEWRLG 190 CSDILNYSGN 200 LMEPPFQSQK 210 KFGTNFTKLE 220 KKTIRGKKYD SDSDDD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0030496 midbody
Cellular Component GO:0005634 nucleus
Biological Process GO:0000226 microtubule cytoskeleton organization

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.