Search Results
Overview
| Uniprot ID | F1SU38 |
|---|---|
| Protein Name | Urokinase-type plasminogen activator |
| Gene Name | PLAU |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 296 | LLKIRTDKGQCAQPS |
Function
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin
Protein Sequence
10
MRVLRACLLL
20
CVLVVSDSKG
30
SHELHQESGA
40
SNCGCLNGGK
50
CVSYKYFSNI
60
QRCSCPKKFQ
70
GEHCEIDTSQ
80
TCFEGNGHSY
90
RGKANTNTGG
100
RPCLPWNSAT
110
VLLNTYHAHR
120
PDALQLGLGK
130
HNYCRNPDNQ
140
RRPWCYVQVG
150
LKQLVQECMV
160
PNCSGGESHR
170
PAYDGKNPFS
180
TPEKVEFQCG
190
QKALRPRFKI
200
VGGKSTTIEN
210
QPWFAAIYRR
220
HRGGSVTYVC
230
GGSLISPCWV
240
VSATHCFINY
250
QQKEDYIVYL
260
GRQTLHSSTR
270
GEMEFEVEKL
280
ILHEDYSADS
290
LAHHNDIALL
300
KIRTDKGQCA
310
QPSRSIQTIC
320
LPPVNGDAHF
330
GASCEIVGFG
340
KEDPSDYLYP
350
EQLKMTVVKL
360
VSHRECQQPH
370
YYGSEVTTKM
380
LCAADPQWKT
390
DSCQGDSGGP
400
LVCSTQGRLT
410
LTGIVSWGRE
420
CAMKDKPGVY
430
TRVSHFLTWI
440
HTHVGGENGL
AH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005615 | extracellular space |
| Molecular Function | GO:0048018 | receptor ligand activity |
| Molecular Function | GO:0004252 | serine-type endopeptidase activity |
| Biological Process | GO:0031639 | plasminogen activation |
| Biological Process | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway |
| Biological Process | GO:0033628 | regulation of cell adhesion mediated by integrin |
| Biological Process | GO:2001044 | regulation of integrin-mediated signaling pathway |
| Biological Process | GO:0014910 | regulation of smooth muscle cell migration |
| Biological Process | GO:2000097 | regulation of smooth muscle cell-matrix adhesion |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.