Search Results
Overview
| Uniprot ID | F2Z3R4 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | Nfix |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 276 | PPSTSTTKRPKSIDD |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
MYSPYCLTQD
20
EFHPFIEALL
30
PHVRAFSYTW
40
FNLQARKRKY
50
FKKHEKRMSK
60
DEERAVKDEL
70
LGEKPEIKQK
80
WASRLLAKLR
90
KDIRPEFRED
100
FVLTITGKKP
110
PCCVLSNPDQ
120
KGKIRRIDCL
130
RQADKVWRLD
140
LVMVILFKGI
150
PLESTDGERL
160
YKSPQCSNPG
170
LCVQPHHIGV
180
TIKELDLYLA
190
YFVHTPESGQ
200
SDSSNQQGDA
210
DIKPLPNGHL
220
SFQDCFVTSG
230
VWNVTELVRV
240
SQTPVATASG
250
PNFSLADLES
260
PSYYNINQVT
270
LGRRSITSPP
280
STSTTKRPKS
290
IDDSEMESPV
300
DDVFYPGTGR
310
SPAAGSSQSS
320
GWPNDVDAGP
330
ASLKKSGKLD
340
FCSALSSQGS
350
SPRMAFTHHP
360
LPVLAGVRPG
370
SPRATASALH
380
FPSTSIIQQS
390
SPYFTHPTIR
400
YHHHHGQDSL
410
KEFVQFVCSD
420
GSGQATGQPN
430
GSGQGKVPGS
440
FLLPPPPPVA
450
RPVPLPMPDS
460
KTTSTAPDGA
470
ALTPPSPSFT
480
TTGASSANRF
490
VSIGSRDSNF
500
LNIPQQSQSW
FL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.