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Overview

Uniprot IDF2Z3T8
Protein NameGuanine nucleotide-binding protein subunit gamma
Gene NameGng5
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
10 SSSVAAMKKVVQQLR
11 SSVAAMKKVVQQLRL
26 EAGLNRVKVSQAAAD

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

Protein Sequence

10 SGSSSVAAMK 20 KVVQQLRLEA 30 GLNRVKVSQA 40 AADLKQFCLQ 50 NAQHDPLLTG 60 VSSSTNPFRP QKVCSFL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005834 heterotrimeric G-protein complex
Molecular Function GO:0031681 G-protein beta-subunit binding
Biological Process GO:0007186 G protein-coupled receptor signaling pathway

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.