Search Results
Overview
| Uniprot ID | F2Z572 |
|---|---|
| Protein Name | Ribose-phosphate pyrophosphokinase 1 |
| Gene Name | PRPS1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 176 | SPDAGGAKRYVTSIA |
| 18 | SHQDLSQKIADRLGL |
| 195 | VDFALIHKERKKANE |
| 213 | MVLVGDVKDRVAILV |
| 29 | RLGLELGKVVTKKFS |
Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis
Protein Sequence
10
MPNIKIFSGS
20
SHQDLSQKIA
30
DRLGLELGKV
40
VTKKFSNQET
50
CVEIGESVRG
60
EDVYIVQSGC
70
GEINDNLMEL
80
LIMINACKIA
90
SASRVTAVIP
100
CFPYARQDKK
110
DKSRAPISAK
120
LVANMLSVAG
130
ADHIITMDLH
140
ASQIQGFFDI
150
PVDNLYAEPA
160
VLKWIRENIS
170
EWRNCTIVSP
180
DAGGAKRYVT
190
SIADRLNVDF
200
ALIHKERKKA
210
NEVDRMVLVG
220
DVKDRVAILV
230
DDMADTCGTI
240
CHAADKLLSA
250
GATRVYAILT
260
HGIFSGPAIS
270
RINNACFEAV
280
VVTNTIPQED
290
KMKHCSKIQV
300
IDISMILAEA
310
IRRTHNGESV
SYLFSHVPL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0002189 | ribose phosphate diphosphokinase complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016301 | kinase activity |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0004749 | ribose phosphate diphosphokinase activity |
| Biological Process | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process |
| Biological Process | GO:0046101 | hypoxanthine biosynthetic process |
| Biological Process | GO:0007399 | nervous system development |
| Biological Process | GO:0006164 | purine nucleotide biosynthetic process |
| Biological Process | GO:0009156 | ribonucleoside monophosphate biosynthetic process |
| Biological Process | GO:0034418 | urate biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.