Search Results

Overview

Uniprot IDF2Z5M2
Protein NameProtein S100-A10
Gene Name-
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
23 FHKFAGDKGYLTKED
28 GDKGYLTKEDLRVLM
54 KDPLAVDKIMKDLDQ
57 LAVDKIMKDLDQCRD

Function

Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase

Protein Sequence

10 MPSQMEHAME 20 TMMFTFHKFA 30 GDKGYLTKED 40 LRVLMEKEFP 50 GFLENQKDPL 60 AVDKIMKDLD 70 QCRDGKVGFQ 80 SFFSLIAGLT 90 IACNDYFVVH MKQKGKK

Gene Ontology

Classification GO ID Description
Cellular Component GO:1990665 AnxA2-p11 complex
Cellular Component GO:0009986 cell surface
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0045121 membrane raft
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0048306 calcium-dependent protein binding
Molecular Function GO:0042803 protein homodimerization activity
Molecular Function GO:0044325 transmembrane transporter binding
Biological Process GO:0001765 membrane raft assembly
Biological Process GO:0042789 mRNA transcription by RNA polymerase II
Biological Process GO:0051894 positive regulation of focal adhesion assembly
Biological Process GO:0010756 positive regulation of plasminogen activation
Biological Process GO:0051496 positive regulation of stress fiber assembly
Biological Process GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0050767 regulation of neurogenesis
Biological Process GO:0006900 vesicle budding from membrane

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.