Search Results
Overview
| Uniprot ID | F2Z5Q5 |
|---|---|
| Protein Name | Ras-related GTP-binding protein |
| Gene Name | RRAGA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 142 | DQRDLIFKEREEDLR |
| 230 | RDVHRFEKISNIIKQ |
| 236 | EKISNIIKQFKLSCS |
Function
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade
Protein Sequence
10
MPNTAMKKKV
20
LLMGKSGSGK
30
TSMRSIIFAN
40
YIARDTRRLG
50
ATIDVEHSHV
60
RFLGNLVLNL
70
WDCGGQDTFM
80
ENYFTSQRDN
90
IFRNVEVLIY
100
VFDVESRELE
110
KDMHYYQSCL
120
EAILQNSPDA
130
KIFCLVHKMD
140
LVQEDQRDLI
150
FKEREEDLRR
160
LSRPLECACF
170
RTSIWDETLY
180
KAWSSIVYQL
190
IPNVQQLEMN
200
LRNFAQIIEA
210
DEVLLFERAT
220
FLVISHYQCK
230
EQRDVHRFEK
240
ISNIIKQFKL
250
SCSKLAASFQ
260
SMEVRNSNFA
270
AFIDIFTSNT
280
YVMVVMSDPS
290
IPSAATLINI
300
RNARKHFEKL
310
ERVDGPKHSL
LMR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:1990877 | FNIP-folliculin RagC/D GAP |
| Cellular Component | GO:1990130 | GATOR1 complex |
| Cellular Component | GO:1990131 | Gtr1-Gtr2 GTPase complex |
| Cellular Component | GO:0005765 | lysosomal membrane |
| Cellular Component | GO:0005764 | lysosome |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0051219 | phosphoprotein binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0043495 | protein-membrane adaptor activity |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0034198 | cellular response to amino acid starvation |
| Biological Process | GO:0071230 | cellular response to amino acid stimulus |
| Biological Process | GO:0009267 | cellular response to starvation |
| Biological Process | GO:0042593 | glucose homeostasis |
| Biological Process | GO:0035556 | intracellular signal transduction |
| Biological Process | GO:0010507 | negative regulation of autophagy |
| Biological Process | GO:1904263 | positive regulation of TORC1 signaling |
| Biological Process | GO:0061462 | protein localization to lysosome |
| Biological Process | GO:0072657 | protein localization to membrane |
| Biological Process | GO:0033209 | tumor necrosis factor-mediated signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.