Search Results

Overview

Uniprot IDF2Z5V2
Protein NameSmall nuclear ribonucleoprotein G
Gene NameSNRPG
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
10 KAHPPELKKFMDKKL
20 MDKKLSLKLNGGRHV
3 *****MSKAHPPELK

Function

Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing

Protein Sequence

10 MSKAHPPELK 20 KFMDKKLSLK 30 LNGGRHVQGI 40 LRGFDPFMNL 50 VIDECVEMAT 60 SGQQNNIGMV 70 VIRGNSIIML EALERV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0071013 catalytic step 2 spliceosome
Cellular Component GO:0005829 cytosol
Cellular Component GO:0043186 P granule
Cellular Component GO:0071011 precatalytic spliceosome
Cellular Component GO:0034719 SMN-Sm protein complex
Cellular Component GO:0097526 spliceosomal tri-snRNP complex
Cellular Component GO:0005685 U1 snRNP
Cellular Component GO:0005689 U12-type spliceosomal complex
Cellular Component GO:0005686 U2 snRNP
Cellular Component GO:0071004 U2-type prespliceosome
Cellular Component GO:0005687 U4 snRNP
Cellular Component GO:0005682 U5 snRNP
Molecular Function GO:0003723 RNA binding
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0000387 spliceosomal snRNP assembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.