Search Results
Overview
| Uniprot ID | F4Y595 |
|---|---|
| Protein Name | Histidine kinase/HSP90-like ATPase domain-containing protein |
| Gene Name | LOC543319 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 483 | ENSPFLEKLKKKGYE |
| 55 | RFESLTDKSKLDAQP |
Function
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function
Protein Sequence
10
MATETETFAF
20
QAEINQLLSL
30
IINTFYSNKE
40
IFLRELISNS
50
SDALDKIRFE
60
SLTDKSKLDA
70
QPELFIHIIP
80
DKATSTLTIV
90
DSGIGMTKSD
100
LVNNLGTIAR
110
SGTKEFMEAL
120
AAGADVSMIG
130
QFGVGFYSAY
140
LVAERVVVTT
150
KHNDDEQYVW
160
ESQAGGSFTV
170
TRDTSGEQLG
180
RGTKMVLYLK
190
DDQMEYLEER
200
RIKDLVKKHS
210
EFISYPISLW
220
TEKTTEKEIS
230
DDEDEEEKKD
240
TEEGKVEDVD
250
EEKEEKEKKK
260
KKIKEVSHEW
270
NLVNKQKPIW
280
MRKPEEINKE
290
EYAAFYKSLT
300
NDWEEHLAVK
310
HFSVEGQLEF
320
KAVLFVPKRA
330
PFDLFDNKKK
340
ANNIKLYVRR
350
VFIMDNCEEL
360
IPEYLSFVKG
370
IVDSEDLPLN
380
ISRETLQQNK
390
ILKVIRKNLV
400
KKCIELFFEI
410
AENKEDYNKF
420
YEAFSKNLKL
430
GIHEDSQNRT
440
KIAELLRYHS
450
TKSGDELTSL
460
KDYVTRMKEG
470
QNEIYYITGE
480
SKKAVENSPF
490
LEKLKKKGYE
500
VIYMVDAIDE
510
YAIGQLKEFE
520
GKKLVSATKE
530
GLKLDESEDE
540
KKKQEELKEK
550
FEGLCKVIKE
560
VLGDKVEKVI
570
VSDRVVDSPC
580
CLVTGEYGWT
590
ANMERIMKAQ
600
ALRDSSMAGY
610
MSSKKTMEIN
620
PENAIMDELR
630
KRADADKNDK
640
SVKDLVMLLF
650
ETSLLTSGFS
660
LEDPNTFGTR
670
IHRMLKLGLS
680
IDEDDEAPEN
690
DTDMPPLEDD
700
AGESKMEEVD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0140662 | ATP-dependent protein folding chaperone |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0034605 | cellular response to heat |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0050821 | protein stabilization |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.