Search Results
Overview
| Uniprot ID | F6PXU8 |
|---|---|
| Protein Name | Decapping nuclease |
| Gene Name | DXO |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 21 | RVAEPCNKLPRPAPS |
Function
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA
Protein Sequence
10
MEPRGTKRGA
20
AKIRVAEPCN
30
KLPRPAPSLP
40
TDPALYSGPF
50
PFYRRPSELG
60
CFSLDTQRQY
70
HGDARALRYY
80
SPPPTNGQSP
90
NFDLRDGYPD
100
RYQTRDEEVQ
110
ERLDHLLRWL
120
LEHRGQLEGR
130
LGNHPLLFSG
140
EVDCTDPQAP
150
STQPPACYVE
160
LKTSKEMHSP
170
GQWKSFYRHK
180
LLKWWAQSFL
190
LGVPNVVAGF
200
RTPEGFICSL
210
KTFPTMEMFE
220
HVRNDRDGWN
230
PSVCMNFCAA
240
FLSFAQNTVV
250
QDDPRLVYLF
260
SWEPGGPVTV
270
SEHRDAPHAF
280
LPTWYVEAMT
290
QDLPPPPKTP
SPKD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004518 | nuclease activity |
| Molecular Function | GO:0000166 | nucleotide binding |
| Molecular Function | GO:0003723 | RNA binding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.