Search Results

Overview

Uniprot IDF7EY92
Protein Name-
Gene NameMbd3
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
41 FYYSPSGKKFRSKPQ

Function

No function data available.

Protein Sequence

10 MERKRWECPA 20 LPQGWEREEV 30 PRRSGLSAGH 40 RDVFYYSPSG 50 KKFRSKPQLA 60 RYLGGSMDLS 70 TFDFRTGKML 80 MNKMNKSRQR 90 VRYDSSNQVK 100 ALAKHLPGPS 110 NPSWTPVGAA 120 RCRVFSPQGK 130 PDLNTALPVR 140 QTASIFKQPV 150 TKITNHPSNK 160 VKSDPQKAVD 170 QPRQLFWEKK 180 LSGLSAFDIA 190 EELVRTMDLP 200 KGLQGVGPGC 210 TDETLLSAIA 220 SALHTSTLPI 230 TGQLSAAVEK 240 NPGVWLNTAQ 250 PLCKAFMVTD 260 DDIRKQEELV 270 QQVRKRLEEA 280 LMADMLAHVE 290 ELARDGEAPL 300 DKACAEEEEE 310 EEEEEEEEPE PERV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000785 chromatin
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0000792 heterochromatin
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0016581 NuRD complex
Cellular Component GO:0032991 protein-containing complex
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0008327 methyl-CpG binding
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0006346 DNA methylation-dependent constitutive heterochromatin formation
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0048568 embryonic organ development
Biological Process GO:0040029 epigenetic regulation of gene expression
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:1903925 response to bisphenol A
Biological Process GO:0032355 response to estradiol
Biological Process GO:0031667 response to nutrient levels
Biological Process GO:0009888 tissue development
Biological Process GO:0003229 ventricular cardiac muscle tissue development

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.