Search Results
Overview
| Uniprot ID | F7F350 |
|---|---|
| Protein Name | Synapse-associated protein 1 |
| Gene Name | Syap1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 80 | FASAATKKITESVTE |
Function
Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation
Protein Sequence
10
MFRGLSSWLG
20
LKQPEGAAAG
30
EEPPSGDKLS
40
SGAAPPEKSS
50
EGLVEPTEEE
60
EQLTEDPQFL
70
HQAKGLGNYL
80
YSFASAATKK
90
ITESVTETAQ
100
TIKKSVEEGK
110
IDDILDKTII
120
GDFQKEQKKF
130
VEEQHTKKSE
140
AAVPPWVESH
150
DEETIQQQIL
160
ALSADKRNFL
170
RDPPAGVQFN
180
FDFDQMYPVA
190
LVMLQEDELL
200
SKMRFALVPK
210
LVKEEVFWRN
220
YFYRISLIKQ
230
SAQLTALAAQ
240
QQASGKEEKS
250
SSRDDNLPLT
260
EAVRPKTPPV
270
VIKSQLKNQE
280
DEEEISTSPG
290
VSEFVSDAFD
300
ACNLNQEDLR
310
KEMEQLVLDK
320
KQEEATALEE
330
DSTDWEKELQ
340
QELQEYEVVA
350
ESEKRDENWD
360
KEIEKMLQES
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0009898 | cytoplasmic side of plasma membrane |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0030426 | growth cone |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0043204 | perikaryon |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0045211 | postsynaptic membrane |
| Cellular Component | GO:0042734 | presynaptic membrane |
| Cellular Component | GO:0045202 | synapse |
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:0032869 | cellular response to insulin stimulus |
| Biological Process | GO:1990314 | cellular response to insulin-like growth factor stimulus |
| Biological Process | GO:0036120 | cellular response to platelet-derived growth factor stimulus |
| Biological Process | GO:0045600 | positive regulation of fat cell differentiation |
| Biological Process | GO:0071902 | positive regulation of protein serine/threonine kinase activity |
| Biological Process | GO:0048172 | regulation of short-term neuronal synaptic plasticity |
| Biological Process | GO:0038203 | TORC2 signaling |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.