Search Results
Overview
| Uniprot ID | F7FJ14 |
|---|---|
| Protein Name | PC4 and SFRS1-interacting protein |
| Gene Name | Psip1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 135 | ASNEDVTKAADITTP |
| 143 | AADITTPKAARRGRK |
| 16 | DLIFAKMKGYPHWPA |
| 188 | RPAATEVKIPKPRGR |
| 197 | PKPRGRPKVVKQPCP |
| 303 | AHRRNMLKGQHEKEA |
| 406 | LKKIRRFKVSQVIME |
| 91 | IDNNPKVKFSSQQVS |
Function
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis
Protein Sequence
10
MTRDFKPGDL
20
IFAKMKGYPH
30
WPARVDEVPD
40
GAVKPPTNKL
50
PIFFFGTHET
60
AFLGPKDIFP
70
YSENKEKYGK
80
PNKRKGFNEG
90
LWEIDNNPKV
100
KFSSQQVSTK
110
QSNASSDVEA
120
EEKETSVSKE
130
DTDQEEKASN
140
EDVTKAADIT
150
TPKAARRGRK
160
RKAEKQVDTE
170
EAGVVTAATA
180
SNVKASPKRG
190
RPAATEVKIP
200
KPRGRPKVVK
210
QPCPSESDMV
220
IDEDKSKKKG
230
PEEKPPKKQL
240
KKEEEGQKEE
250
EKPRKEPDKK
260
EGKKEVESKR
270
KNLAKPGVTS
280
TSDSEEDDDQ
290
EGEKQKRKGG
300
RNFQAAHRRN
310
MLKGQHEKEA
320
ADRKRKQEEQ
330
METEQQTKDE
340
GKKPEVKKVE
350
KKRETSMDSR
360
LQRIHAEIKN
370
SLKIDNLDVN
380
RCIEALDELA
390
SLQVTMQQAQ
400
KHTEMITTLK
410
KIRRFKVSQV
420
IMEKSTMLYN
430
KFKNMFLVGE
440
GDSVITQVLN
450
KSLAEQRQHE
460
EANKTKDQGK
470
KGPNKKLEKE
480
QTGTKSLNGG
490
SDAQESNHPQ
500
HNGDSAEESK
510
DSREAGSKTK
520
TPGEEREAEV
SLKESTLDN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0003677 | DNA binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000395 | mRNA 5'-splice site recognition |
| Biological Process | GO:0009408 | response to heat |
| Biological Process | GO:0006979 | response to oxidative stress |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.