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Overview

Uniprot IDF7FPA1
Protein NameSynaptosomal-associated protein 29
Gene NameSnap29
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
155 KEAINTSKDQESKYQ

Function

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions

Protein Sequence

10 MSGYPKSYNP 20 FDDDVEDEDT 30 RPAPWKDARD 40 LPDGPDAPID 50 RQQYLRQEVL 60 RRAEATAAST 70 SRSLSLMYES 80 EKIGVASSEE 90 LVRQRGVLEH 100 TEKMVDKMDQ 110 DLKMSQKHIN 120 SIKSVFGGFI 130 NYFKSKPVEP 140 PPEQNGSIVP 150 QPSSRRLKEA 160 INTSKDQESK 170 YQASHPNLRR 180 LHDAELDSVP 190 ASTVNTEVYP 200 KNSSLRAYHQ 210 KIDSNLDELS 220 VGLGRLKDIA 230 LGMQTEIEEQ 240 DDILDRLTTK 250 VDKLDVNIKS TEKKVRQL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000421 autophagosome membrane
Cellular Component GO:0020018 ciliary pocket membrane
Cellular Component GO:0031410 cytoplasmic vesicle
Cellular Component GO:0005829 cytosol
Cellular Component GO:0000139 Golgi membrane
Cellular Component GO:0031201 SNARE complex
Biological Process GO:0016240 autophagosome membrane docking
Biological Process GO:0060271 cilium assembly
Biological Process GO:0015031 protein transport

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.