Search Results
Overview
| Uniprot ID | G3V0I5 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial |
| Gene Name | NDUFV1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 119 | EGEPGTCKDREILRH |
| 219 | KQGKPRLKPPFPADV |
Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I
Protein Sequence
10
MLATRRLLGW
20
SLPARVSTAP
30
KKTSFGSLKD
40
EDRIFTNLYG
50
RHDWRLKGSL
60
SRGDWYKTKE
70
ILLKGPDWIL
80
GEIKTSGLRG
90
RGGAGFPTGL
100
KWSFMNKPSD
110
GRPKYLVVNA
120
DEGEPGTCKD
130
REILRHDPHK
140
LLEGCLVGGR
150
AMGARAAYIY
160
IRGEFYNEAS
170
NLQVAIREAY
180
EAGLIGKNAC
190
GSGYDFDVFV
200
VRGAGAYICG
210
EETALIESIE
220
GKQGKPRLKP
230
PFPADVGVFG
240
CPTTVANVET
250
VAVSPTICRR
260
GGTWFAGFGR
270
ERNSGTKLFN
280
ISGHVNHPCT
290
VEEEMSVPLK
300
ELIEKHAGGV
310
TGGWDNLLAV
320
IPGGSSTPLI
330
PKSVCETVLM
340
DFDALVQAQT
350
GLGTAAVIVM
360
DRSTDIVKAI
370
ARLIEFYKHE
380
SCGQCTPCRE
390
GVDWMNKVMA
400
RFVRGDARPA
410
EIDSLWEISK
420
QIEGHTICAL
430
GDGAAWPVQG
440
LIRHFRPELE
450
ERMQRFAQQH
QARQAAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0045271 | respiratory chain complex I |
| Molecular Function | GO:0051539 | 4 iron, 4 sulfur cluster binding |
| Molecular Function | GO:0010181 | FMN binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0051287 | NAD binding |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Molecular Function | GO:0016491 | oxidoreductase activity |
| Biological Process | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone |
Reference
PMID: N/A