Search Results
Overview
| Uniprot ID | G3V6D9 |
|---|---|
| Protein Name | Na(+)/H(+) exchange regulatory cofactor NHE-RF |
| Gene Name | Nherf2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 29 | GFHLHGEKGRRGQFI |
Function
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression
Protein Sequence
10
MAAPESLRPR
20
LCRLVRGEQG
30
YGFHLHGEKG
40
RRGQFIRRVE
50
PGSPAEAAAL
60
RAGDRLVEVN
70
GVNVEGETHH
80
QVVQRIKAVE
90
GQTQLLVVDK
100
ETDEELCRRQ
110
LTCTEEMAHR
120
GLPPAHNPWE
130
PKPDWACSGS
140
LGSDTGQKDV
150
NGPPRELRPR
160
LCHLRRGPQG
170
YGFNLHSDKS
180
RPGQYIRSVD
190
PGSPASLSGL
200
RAQDRLIEVN
210
GQNVEGLRHA
220
EVVARIKAQE
230
DEARLLVVDP
240
ETDEHFKRLR
250
VVPTEDHVEG
260
PLPSPVTNGT
270
SLAQLNGGSV
280
CSSRSDLPGS
290
EKDNEDGSAW
300
KRDPFQESGL
310
HLSPTAAEAK
320
EKARATRVNK
330
RAPQMDWNRK
REIFSNF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0012505 | endomembrane system |
| Molecular Function | GO:0060090 | molecular adaptor activity |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.