Search Results
Overview
| Uniprot ID | G3V6S3 |
|---|---|
| Protein Name | Calumenin |
| Gene Name | Calu |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 165 | RRFKMADKDGDLIAT |
| 281 | VYESDQDKDGKLTKE |
| 284 | SDQDKDGKLTKEEIV |
| 287 | DKDGKLTKEEIVDKY |
| 70 | QLTPEESKERLGKIV |
| 75 | ESKERLGKIVNKIDG |
| 84 | VNKIDGDKDGFVTVD |
| 98 | DELKGWIKFAQKRWI |
Function
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity
Protein Sequence
10
MDLRQFLMCL
20
SLCTAFALSK
30
PTEKKDRVHH
40
EPQLSDKVHN
50
DAQNFDYDHD
60
AFLGAEEAKS
70
FDQLTPEESK
80
ERLGKIVNKI
90
DGDKDGFVTV
100
DELKGWIKFA
110
QKRWIHEDVE
120
RQWKGHDLNE
130
DGLVSWEEYK
140
NATYSYVLDD
150
PDPDDGFNYK
160
QMMVRDERRF
170
KMADKDGDLI
180
ATKEEFTAFL
190
HPEEYDYMKD
200
IVVQETMEDI
210
DKNADGFIDL
220
EEYIGDMYSH
230
DGNADEPEWV
240
KTEREQFVEF
250
RDKNRDGKMD
260
KEETKDWILP
270
SDYDHAEAEA
280
RHLVYESDQD
290
KDGKLTKEEI
300
VDKYDLFVGS
310
QATDFGEALV
RHDEF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0033018 | sarcoplasmic reticulum lumen |
| Molecular Function | GO:0005509 | calcium ion binding |
| Cellular Component | GO:0005576 | extracellular region |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.