Search Results
Overview
| Uniprot ID | G3V6U3 |
|---|---|
| Protein Name | Alpha-1,3/1,6-mannosyltransferase ALG2 |
| Gene Name | Alg2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 379 | AMEKFIHKPSLKATM |
Function
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate
Protein Sequence
10
MAENLYRTRS
20
RVYSPSVLFL
30
HPDMGIGGAE
40
RLVLDAALAL
50
QEYGCQVKIW
60
TAHYDPNHCF
70
IETRELSVQC
80
AGDWLPRSLG
90
WGGRGAAICS
100
YVRMVFLALY
110
VLFLSGEEFD
120
VVVCDQVSAC
130
IPVFKLARRR
140
KRVLFYCHFP
150
DLLLTQRNSS
160
LKKFYRAPID
170
WIEEYTTGMA
180
DRILVNSQYT
190
ASVFKETFKT
200
LSHRNPDVLY
210
PSLNIGSFDL
220
AVPEKIDDLV
230
PKGKQFLFLS
240
INRYERKKNL
250
PLALSSLVQL
260
RARLPPQEWE
270
KVHLFMAGGY
280
DDRVLENVEH
290
YKELKKIVQE
300
SDLERHVTFL
310
RSFSDRQKIS
320
LLHGCLCVLY
330
TPSNEHFGIV
340
PLEAMYMQCP
350
VIAVNSGGPL
360
ESIVHKVTGF
370
LCEPDPVHFS
380
EAMEKFIHKP
390
SLKATMGLAG
400
KARVAEKFSA
410
DAFADQLYQY
VTKLV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane |
| Cellular Component | GO:0012505 | endomembrane system |
| Molecular Function | GO:0000033 | alpha-1,3-mannosyltransferase activity |
| Molecular Function | GO:0004378 | GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity |
| Molecular Function | GO:0102704 | GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity |
| Biological Process | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process |
| Biological Process | GO:0009101 | glycoprotein biosynthetic process |
| Biological Process | GO:0006487 | protein N-linked glycosylation |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.