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Overview

Uniprot IDG3V705
Protein NamePolyglutamine-binding protein 1
Gene NamePqbp1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
13 ALQTRLAKRGILKHL

Function

No function data available.

Protein Sequence

10 MPLPVALQTR 20 LAKRGILKHL 30 EPEPEEEIIA 40 EDYDDDPVDY 50 EATRIEGLPP 60 SWYKVFDPSC 70 GLPYYWNVET 80 DLVSWLSPHD 90 PNFVVSKSAK 100 KLRNSNADAE 110 DKSERNLEKV 120 DRNHEKSDRS 130 HEKPDRSHEK 140 ADRNHEKSDR 150 ERERNYDKVD 160 RERDRDRERE 170 RAFDKADRED 180 GKDRRHHRRE 190 DLAPYPKNKK 200 ATSRKDEELD 210 PMDPSSYSDA 220 PRGTWSTGLP 230 KRNEAKTGAD 240 TTAAGPLFQQ 250 RPYPSPGAVL 260 RANAEASRSK QQD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0010494 cytoplasmic stress granule
Cellular Component GO:0071598 neuronal ribonucleoprotein granule
Cellular Component GO:0016607 nuclear speck
Molecular Function GO:0003690 double-stranded DNA binding
Molecular Function GO:0043021 ribonucleoprotein complex binding
Biological Process GO:0002218 activation of innate immune response
Biological Process GO:0000380 alternative mRNA splicing, via spliceosome
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0051607 defense response to virus
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0045087 innate immune response
Biological Process GO:0031175 neuron projection development
Biological Process GO:0002230 positive regulation of defense response to virus by host
Biological Process GO:0032481 positive regulation of type I interferon production

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.