Search Results
Overview
| Uniprot ID | G3V715 |
|---|---|
| Protein Name | 5'-AMP-activated protein kinase catalytic subunit alpha-2 |
| Gene Name | Prkaa2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 51 | VKILNRQKIRSLDVV |
Function
No function data available.
Protein Sequence
10
MAEKQKHDGR
20
VKIGHYVLGD
30
TLGVGTFGKV
40
KIGEHQLTGH
50
KVAVKILNRQ
60
KIRSLDVVGK
70
IKREIQNLKL
80
FRHPHIIKLY
90
QVISTPTDFF
100
MVMEYVSGGE
110
LFDYICKHGR
120
VEEVEARRLF
130
QQILSAVDYC
140
HRHMVVHRDL
150
KPENVLLDAQ
160
MNAKIADFGL
170
SNMMSDGEFL
180
RTSCGSPNYA
190
APEVISGRLY
200
AGPEVDIWSC
210
GVILYALLCG
220
TLPFDDEHVP
230
TLFKKIRGGV
240
FYIPEYLNRS
250
IATLLMHMLQ
260
VDPLKRATIK
270
DIREHEWFKQ
280
DLPSYLFPED
290
PSYDANVIDD
300
EAVKEVCEKF
310
ECTESEVMNS
320
LYSGDPQDQL
330
AVAYHLIIDN
340
RRIMNQASEF
350
YLASSPPTGS
360
FMDDSAMHIP
370
PGLKPHPERM
380
PPLIADSPKA
390
RCPLDALNTT
400
KPKSLAVKKA
410
KWHLGIRSQS
420
KPYDIMAEVY
430
RAMKQLDFEW
440
KVVNAYHLRV
450
RRKNPVTGNY
460
VKMSLQLYLV
470
DNRSYLLDFK
480
SIDDEVVEQR
490
SGSSTPQRSC
500
SAAGLHRPRS
510
SVDSSTAENH
520
SLSGSLTGSL
530
TGSTLSSASP
540
RLGSHTMDFF
550
EMCASLITAL
AR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0010494 | cytoplasmic stress granule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity |
| Molecular Function | GO:0004679 | AMP-activated protein kinase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0140823 | histone H2BS36 kinase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004712 | protein serine/threonine/tyrosine kinase activity |
| Biological Process | GO:0006914 | autophagy |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:0042149 | cellular response to glucose starvation |
| Biological Process | GO:0071333 | cellular response to glucose stimulus |
| Biological Process | GO:0034599 | cellular response to oxidative stress |
| Biological Process | GO:0006695 | cholesterol biosynthetic process |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006633 | fatty acid biosynthetic process |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:1903944 | negative regulation of hepatocyte apoptotic process |
| Biological Process | GO:1904262 | negative regulation of TORC1 signaling |
| Biological Process | GO:0010508 | positive regulation of autophagy |
| Biological Process | GO:1903829 | positive regulation of protein localization |
| Biological Process | GO:1990044 | protein localization to lipid droplet |
| Biological Process | GO:0042752 | regulation of circadian rhythm |
| Biological Process | GO:0016241 | regulation of macroautophagy |
| Biological Process | GO:0070507 | regulation of microtubule cytoskeleton organization |
| Biological Process | GO:0062028 | regulation of stress granule assembly |
| Biological Process | GO:0048511 | rhythmic process |
| Biological Process | GO:0016055 | Wnt signaling pathway |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.