Search Results
Overview
| Uniprot ID | G3V7X9 |
|---|---|
| Protein Name | Cyclic AMP-dependent transcription factor ATF-7 |
| Gene Name | Atf7 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 36 | HKHEMTLKFGPARTD |
Function
Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes
Protein Sequence
10
MGDDRPFVCS
20
APGCGQRFTN
30
EDHLAVHKHK
40
HEMTLKFGPA
50
RTDSVIIADQ
60
TPTPTRFLKN
70
CEEVGLFNEL
80
ASSFEHEFKK
90
ASDDDEKKSA
100
AGPLDMSLPS
110
TPDIKVKEEE
120
PVEVDSSPPD
130
SPASCPCSPP
140
LKDKEVATKP
150
VVISTPTPTI
160
VRPGSLPLHL
170
GYDPLHPTLP
180
SPTSVITQAP
190
PSNRQIGSPT
200
GSLPLVMHLA
210
NGQTMPMLPG
220
PPVQMPSVIS
230
LARPVSMVPN
240
IPGIPGPPVN
250
NSGSISPSGH
260
PMPSEAKMRL
270
KATLTHQVSS
280
INGGCGMVVG
290
TASTMVTARP
300
EQNQILIQHP
310
DAPSPAQPQV
320
SPAQPTPSTG
330
GRRRRTVDED
340
PDERRQRFLE
350
RNRAAASRCR
360
QKRKLWVSSL
370
EKKAEELTSQ
380
NIQLSKVPRK
390
AQSQRVLQPQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0035497 | cAMP response element binding |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.