Search Results
Overview
| Uniprot ID | G3V8G6 |
|---|---|
| Protein Name | Hyaluronan and proteoglycan link protein 2 |
| Gene Name | Hapln2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 68 | GTSPPSYKVRWSKVE |
Function
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid
Protein Sequence
10
MPSWIPLPAF
20
CCLLLPWAFT
30
VFHKTLGNPA
40
PHPGPHYLLP
50
PIHEVIHSRR
60
GATATLPCVL
70
GTSPPSYKVR
80
WSKVEPGELR
90
ETLILITNGL
100
HARDYGLLGG
110
RASLRRGHRL
120
DASLIIKNVR
130
LEDEGRYRCE
140
LINGIEDESV
150
ALTLRLEGVV
160
FPYQPSRGRY
170
QFNYFEAKRA
180
CEEQDGRLAT
190
YSQLYQAWTE
200
GLDWCNAGWL
210
LEGSVRYPVL
220
NARAPCGGHG
230
RPGIRSYGPR
240
DRSRDRYDAF
250
CFTSALAGQV
260
FFVPGRLTLS
270
EAHAACRRRG
280
AVVAKVGHLY
290
AAWKFSGLDR
300
CDGGWLADGS
310
VRFPITTPRP
320
RCGGLPDPGV
330
RSFGFPRPQQ
340
AAYGTYCYAE
K
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0005540 | hyaluronic acid binding |
| Biological Process | GO:0007155 | cell adhesion |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.