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Overview

Uniprot IDG3V8K2
Protein NameGuanine nucleotide-binding protein subunit gamma
Gene NameGng3
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
18 MSIGQARKMVEQLKI
2 ******MKGETPVNS

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

Protein Sequence

10 MKGETPVNST 20 MSIGQARKMV 30 EQLKIEASLC 40 RIKVSKAAAD 50 LMTYCDAHAC 60 EDPLITPVPT 70 SENPFREKKF FCALL

Gene Ontology

Classification GO ID Description
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Cellular Component GO:0044297 cell body
Cellular Component GO:0030425 dendrite
Cellular Component GO:0005834 heterotrimeric G-protein complex
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0045202 synapse
Molecular Function GO:0031681 G-protein beta-subunit binding
Biological Process GO:0007186 G protein-coupled receptor signaling pathway

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.