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Overview

Uniprot IDG3V996
Protein Name-
Gene NameLetmd1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
209 SALVSNEKLRWHLED

Function

No function data available.

Protein Sequence

10 MALSRVCWSR 20 AALWGSTVAP 30 GPFVTRRLQL 40 GRSGPAWRAP 50 RSSKLHLSPK 60 ADVKNLISYV 70 VTKTRAINGT 80 YHRFLGRHFP 90 RFYALYTTFI 100 KGIQMLWADA 110 KKARRIKADM 120 WKQNLKFHQL 130 SYREMEHLRQ 140 FRRDITKCLF 150 IGLISIPPFA 160 NYLVFLLMYL 170 FPRQLLVKHF 180 WTPKQQIDFL 190 DIYHGFRRRS 200 HLEIITHLRR 210 ASALVSNEKL 220 RWHLEDLCTK 230 VQNGTHPTAQ 240 DILALRDCFS 250 TYPLGFSQLQ 260 ASQMRALSQA 270 MLLTPYLPPP 280 LLRWRLKSHT 290 AVIHQLDRAL 300 AKLGTGHLTP 310 QEVRSACYLR 320 GLNSTHTSDD 330 RCRTWLGEWL 340 HISCSLKEAE 350 LSLLLHNVVL 360 LSTNYLETRR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005634 nucleus
Molecular Function GO:0060090 molecular adaptor activity
Molecular Function GO:0043022 ribosome binding
Biological Process GO:0006754 ATP biosynthetic process
Biological Process GO:0055074 calcium ion homeostasis
Biological Process GO:0010467 gene expression
Biological Process GO:0006954 inflammatory response
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0038061 non-canonical NF-kappaB signal transduction
Biological Process GO:0006909 phagocytosis
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:1903409 reactive oxygen species biosynthetic process
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0050764 regulation of phagocytosis
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0034142 toll-like receptor 4 signaling pathway

Reference

[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.