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Overview

Uniprot IDH0UUK1
Protein Name40S ribosomal protein S8
Gene NameRps8
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
128 LGRKKGAKLTPEEEE
37 GRPAANTKIGPRRIH

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MGISRDNWHK 20 RRKTGGKRKP 30 YHKKRKYELG 40 RPAANTKIGP 50 RRIHTVRVRG 60 GNKKYRALRL 70 DVGNFSWGSE 80 CCTRKTRIID 90 VVYNASNNEL 100 VRTKTLVKNC 110 IVLIDSTPYR 120 QWYESHYALP 130 LGRKKGAKLT 140 PEEEEILNKK 150 RSKKIQKKYD 160 ERKKNAKISS 170 LLEEQFQQGK 180 LLACIASRPG 190 QCGRADGYVL 200 EGKELEFYLR KIKARKGK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0022627 cytosolic small ribosomal subunit
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0006412 translation

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.