Search Results
Overview
| Uniprot ID | H0UXK6 |
|---|---|
| Protein Name | T-complex protein 1 subunit epsilon |
| Gene Name | CCT5 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 265 | PKPKTKHKLDVTSVE |
| 483 | EVRARQVKEANPALG |
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia
Protein Sequence
10
MTSVGTLAFD
20
EYGRPFLIIK
30
DQERKTRLMG
40
LEALKSHIMA
50
AKAVANTMRT
60
SLGPNGLDKM
70
MVDKDGDVTV
80
TNDGATILSM
90
MDVDHQIAKL
100
MVELSKSQDD
110
EIGDGTTGVV
120
VLAGALLEEA
130
EQLLDRGIHP
140
IRIADGYEQA
150
ARIAIEHLDK
160
ISASVFVDTK
170
ETESLIQTAK
180
TTLGSKVVNS
190
CHRQMAEIAV
200
NAVLTVADME
210
RRDVDFELIK
220
VEGKVGGRLE
230
DTKLIKGVIV
240
DKDFSHPQMP
250
KKVENAKIAI
260
LTCPFEPPKP
270
KTKHKLDVTS
280
VEDYKALQKY
290
EKEKFEEMIQ
300
QIKETGANLA
310
ICQWGFDDEA
320
NHLLLQNSLP
330
AVRWVGGPEI
340
ELIAIATGGR
350
IVPRFSELTP
360
EKLGFAGLVQ
370
EISFGTTKDK
380
MLVIEQCKNS
390
RAVTIFIRGG
400
NKMIIEEAKR
410
SLHDALCVIR
420
NLIRDNRVVY
430
GGGAAEISCA
440
LAVSQEADKC
450
PTLEQYAMRA
460
FADALEVIPM
470
ALAENSGMNP
480
IQTMTEVRAR
490
QVKEANPALG
500
IDCLHKGTND
510
MKQQHVIETL
520
IGKKQQISLA
530
TQMVRMILKI
540
DDIRKPGESE
E
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0044297 | cell body |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005832 | chaperonin-containing T-complex |
| Cellular Component | GO:0005874 | microtubule |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0140662 | ATP-dependent protein folding chaperone |
| Molecular Function | GO:0048487 | beta-tubulin binding |
| Molecular Function | GO:0031681 | G-protein beta-subunit binding |
| Molecular Function | GO:0003730 | mRNA 3'-UTR binding |
| Molecular Function | GO:0048027 | mRNA 5'-UTR binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0050821 | protein stabilization |
| Biological Process | GO:0009615 | response to virus |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.