Search Results
Overview
| Uniprot ID | H0UYU0 |
|---|---|
| Protein Name | mRNA m(6)A methyltransferase |
| Gene Name | METTL3 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 27 | ERLQRRRKQDSGHLD |
Function
No function data available.
Protein Sequence
10
MSDTWSSIQA
20
HKKQLDSLRE
30
RLQRRRKQDS
40
GHLDLRNPEA
50
ALSPTFRSDS
60
PVPPAPVSGG
70
PKSSTVSVVP
80
ELATDPELEK
90
KLLHHLSDLT
100
LTLPTDAVSI
110
CHAISTPDAP
120
ATQDGVESLL
130
QKFAAQELIE
140
VKRGLLQDDA
150
HPTLVTYADH
160
SKLSAMMGAV
170
AEKKGPGEVA
180
GTVTGQKRRA
190
EQDSATVAAF
200
ASSLASGLAS
210
SASEPAKEPA
220
KKSRKHAASD
230
VDLEIESLLN
240
QQSTKEQQSK
250
KVSQEILELL
260
NTTTAKEQSI
270
VEKFRSRGRA
280
QVQEFCDYGT
290
KEECMKASDA
300
DRPCRKLHFR
310
RIINKHTDES
320
LGDCSFLNTC
330
FHMDTCKYVH
340
YEIDACMDSE
350
GSGSNDHTPS
360
QELALTQSVG
370
GDSSADRLFP
380
PQWICCDIRY
390
LDVSILGKFA
400
VVMADPPWDI
410
HMELPYGTLT
420
DDEMRRLNIP
430
VLQDDGFLFL
440
WVTGRAMELG
450
RECRTGHWLN
460
HGKEHCLVGV
470
KGNPQGFNQG
480
LDCDVIVAEV
490
RSTSHKPDEI
500
YGMIERLSPG
510
TRKIELFGRP
520
HNVQPNWITL
530
GNQLDGIHLL
540
DPDVVARFKQ
550
RYPDGIISKP
KNL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0036396 | RNA N6-methyladenosine methyltransferase complex |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0001734 | mRNA m(6)A methyltransferase activity |
| Molecular Function | GO:1990931 | mRNA N6-methyladenosine dioxygenase activity |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:1904047 | S-adenosyl-L-methionine binding |
| Biological Process | GO:0034644 | cellular response to UV |
| Biological Process | GO:0006974 | DNA damage response |
| Biological Process | GO:0009048 | dosage compensation by inactivation of X chromosome |
| Biological Process | GO:0016556 | mRNA modification |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway |
| Biological Process | GO:1903679 | positive regulation of cap-independent translational initiation |
| Biological Process | GO:0031053 | primary miRNA processing |
| Biological Process | GO:0001510 | RNA methylation |
| Biological Process | GO:0043489 | RNA stabilization |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.