Search Results
Overview
| Uniprot ID | H0UZ06 |
|---|---|
| Protein Name | - |
| Gene Name | VEZF1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 376 | RLWEEAVKARKKEAA |
Function
Transcriptional regulator. Acts as a transcriptional activator that binds to purine-rich GAGA sites found in the promoter of many genes including insulin I and II and islet amyloid polypeptide
Protein Sequence
10
MQTSGRLTDL
20
RNNWQAHEAS
30
HHQQQAAQNS
40
LLPLLSSAVE
50
PPDQKPLLPI
60
PITQKPQAAP
70
ETLKDAIGIK
80
KEKPKTSFVC
90
TYCSKAFRDS
100
YHLRRHESCH
110
TGIKLVSRSK
120
KTPTTVVPLI
130
STMAGDSSRT
140
SLVSTIAGIL
150
STVTTSSSGT
160
NPSSSASTTA
170
MPVTQSVKKP
180
SKPVKKNHAC
190
EMCGKAFRDV
200
YHLNRHKLSH
210
SDEKPFECPI
220
CNQRFKRKDR
230
MTYHVRSHEG
240
GITKPYTCSV
250
CGKGFSRPDH
260
LSCHVKHVHS
270
TERPFKCQTC
280
TAAFATKDRL
290
RTHMVRHEGK
300
VSCNICGKLL
310
SAAYITSHLK
320
THGQSQSINC
330
NTCKQGISKT
340
CMSEETSSQK
350
QQQQQQQQQQ
360
QQQQQQQQHW
370
PGKQVETLRL
380
WEEAVKARKK
390
EAANLCQTST
400
AATTPVTLTT
410
PFNITSSVSS
420
GTMSNPVTVA
430
AAMSMRSPVN
440
VSSAVNITSP
450
MNIGHPVTIT
460
SPLSMTSPLT
470
LTTPVNLPTP
480
VTAPVNIAHP
490
VTITSPMNLP
500
TPMTLAAPLN
510
IAMRPVESMP
520
FLPQALPTSP
PW
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045603 | positive regulation of endothelial cell differentiation |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.