Search Results
Overview
| Uniprot ID | H0UZK8 |
|---|---|
| Protein Name | Thioredoxin domain-containing protein 17 |
| Gene Name | TXNDC17 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 78 | VGEKSDWKDPNNDFR |
Function
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide
Protein Sequence
10
MASYVEVSVS
20
GFEEFNRAVA
30
EHPGKTIFAY
40
FSGSKDAGGK
50
SWCPDCVQAE
60
PVVREGLKHV
70
SEGCVFIYCQ
80
VGEKSDWKDP
90
NNDFRKKLKI
100
TAVPTLLKYG
110
TPQKLVESEC
120
LQENLVEMLF
SED
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0004601 | peroxidase activity |
| Molecular Function | GO:0047134 | protein-disulfide reductase [NAD(P)H] activity |
| Biological Process | GO:0033209 | tumor necrosis factor-mediated signaling pathway |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.