Search Results
Overview
| Uniprot ID | H0V0P2 |
|---|---|
| Protein Name | Alpha-adducin |
| Gene Name | ADD1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 474 | KSKTKWTKEDGHRTS |
Function
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin
Protein Sequence
10
MNGDTRAAVV
20
TSPPPTTAPH
30
KERYFDRVDE
40
NNPEYLRERN
50
MAPDLRQDFN
60
MMEQKKRVSM
70
ILQSPAFCEE
80
LESMIQEQFK
90
KGKNPTGLLA
100
LQQIADFMTA
110
NVPSVYPAAP
120
QGGMAALNMS
130
LGMVTPVNDL
140
RGSDSIAYDK
150
GEKLLRCKLA
160
AFYRLADLFG
170
WSQLIYNHIT
180
TRVNSEQEHF
190
LIVPFGLLYS
200
EVTASSLVKI
210
NLQGDVVDRG
220
STNLGVNQAG
230
FTLHSAIYAA
240
RPDVRCIVHI
250
HTPAGAAVSA
260
MKCGLLPISP
270
EALSLGEVAY
280
HDYHGILVDE
290
EEKVLIQKNL
300
GPKSKVLILR
310
NHGLVSVGES
320
IEEAFYYIHN
330
LVVACEIQVR
340
TLASSGGPDN
350
LVLLDPGKYK
360
AKSRFPGPPV
370
GEGSGSPPKW
380
QIGEQEFEAL
390
MRMLDNLGYR
400
TGYPYRYPAL
410
REKSKKYSDV
420
EAPASVTGYS
430
FASDGDSGTC
440
SPLRHSFQKQ
450
QREKTRWLNS
460
GRAEEASEEG
470
QNGSSPKSKT
480
KWTKEDGHRT
490
STSAVPNLFV
500
PLNTNPKEVQ
510
EMRNKIREQN
520
LQDIKTAGPQ
530
SQVLCGVVMD
540
RSLVQGELVT
550
ASKAIIEKEY
560
QPHVIVSTAG
570
PNPFQALTDR
580
ELEEYRREVE
590
RKQKGSEENL
600
GDSREQKEKS
610
LPDQPAEPHT
620
PPSTPVKLEE
630
DLPQELPSAD
640
DSDATTLKPT
650
LPDLSPDEPS
660
EALGFPPVQE
670
EEEEEAPSIR
680
QPPTAVEPEP
690
ASPPMAEKVA
700
SPAAEEGTAM
710
DPSSDGSPGK
720
SPSKKKKKFR
730
TPSFLKKSKK
RDS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0014069 | postsynaptic density |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Biological Process | GO:0051016 | barbed-end actin filament capping |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:1903393 | positive regulation of adherens junction organization |
| Biological Process | GO:1903142 | positive regulation of establishment of endothelial barrier |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.