Search Results
Overview
| Uniprot ID | H0V0Z1 |
|---|---|
| Protein Name | Pleiotropic regulator 1 |
| Gene Name | PLRG1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 511 | SWKPEIIKRKRF*** |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs
Protein Sequence
10
MVEEVQKHSV
20
HTLVFRSLKR
30
THDMFVADNG
40
KPVPLDEESH
50
KRKMAIKLRN
60
EYGPVLHMPT
70
SKENLKEKGP
80
QNATDSYGQK
90
QYPANQGQEV
100
EYVVTGTHPY
110
PPGPGVALTA
120
DTKVQRMPSE
130
SAAQSLAVAS
140
PSPQARTDTN
150
RTTSGGSEYR
160
HPGASERAQP
170
AGVNSMVMET
180
GNTKNSALMA
190
KKAPTMPKPQ
200
WHPPWKLYRV
210
ISGHLGWVRC
220
IAVEPGNQWF
230
VTGSADRTIK
240
IWDLASGKLK
250
LSLTGHISTV
260
RGVIVSTRSP
270
YLFSCGEDKQ
280
VKCWDLEYNK
290
VIRHYHGHLS
300
AVYGLDLHPT
310
IDVLVTCSRD
320
STARIWDVRT
330
KASVHTLSGH
340
TNAVATVRCQ
350
AAEPQIITGS
360
HDTTIRLWDL
370
VAGKTRVTLT
380
NHKKSVRAVV
390
LHPRHYTFAS
400
GSPDNIKQWK
410
FPDGSFIQNL
420
SGHNAIINTL
430
TVNSDGVLVS
440
GADNGTMHLW
450
DWRTGYNFQR
460
VHAAVQPGSL
470
DSESGIFACA
480
FDQSESRLLT
490
AEADKTIKVY
500
REDDTATEET
510
HPVSWKPEII
KRKRF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005662 | DNA replication factor A complex |
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0031965 | nuclear membrane |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0000974 | Prp19 complex |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.