Overview
| Uniprot ID | H0V1L6 |
|---|
| Protein Name | 40S ribosomal protein S6 |
|---|
| Gene Name | LOC134475217 |
|---|
| Organism | Cavia porcellus |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 143 |
KRASRIRKLFNLSKE |
| 79 |
RVRLLLSKGHSCYRP |
Function
Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome
Protein Sequence
10
MKLNISFPAT
20
GCQKLIEVDD
30
ERKLRTFYEK
40
RMATEVAADS
50
LGEEWKGYVV
60
RISGGNDKQG
70
FPMKQGVLTH
80
GRVRLLLSKG
90
HSCYRPRRTG
100
ERKRKSVRGC
110
IVDANLSVLN
120
LVIVKKGEKD
130
IPGLTDTTVP
140
RRLGPKRASR
150
IRKLFNLSKE
160
DDVRQYVVRK
170
PLNKEGKKPR
180
TKAPKIQRLV
190
TPRVLQHKRR
200
RIALKKQRTK
210
KNKEEAAEYA
220
KLLAKRMKEA
230
KEKRQEQIAK
240
RRRLSSLRAS
TSKSESSQK
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:1990904 |
ribonucleoprotein complex |
| Cellular Component |
GO:0005840 |
ribosome |
| Molecular Function |
GO:0003735 |
structural constituent of ribosome |
| Biological Process |
GO:0042254 |
ribosome biogenesis |
| Biological Process |
GO:0006412 |
translation |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.