Search Results
Overview
| Uniprot ID | H0V2B3 |
|---|---|
| Protein Name | Elongation factor 1-alpha |
| Gene Name | EEF1A1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 179 | KEVSTYIKKIGYNPD |
| 255 | LPLQDVYKIGGIGTV |
| 392 | KKLEDGPKFLKSGDA |
| 439 | TVAVGVIKAVDKKAA |
| 44 | RTIEKFEKEAAEMGK |
Function
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Protein Sequence
10
MGKEKTHINI
20
VVIGHVDSGK
30
STTTGHLIYK
40
CGGIDKRTIE
50
KFEKEAAEMG
60
KGSFKYAWVL
70
DKLKAERERG
80
ITIDISLWKF
90
ETSKYYVTII
100
DAPGHRDFIK
110
NMITGTSQAD
120
CAVLIVAAGV
130
GEFEAGISKN
140
GQTREHALLA
150
YTLGVKQLIV
160
GVNKMDSTEP
170
PYSQKRYEEI
180
VKEVSTYIKK
190
IGYNPDTVAF
200
VPISGWNGDN
210
MLEPSANMPW
220
FKGWKVTRKD
230
GNASGTTLLE
240
ALDCILPPTR
250
PTDKPLRLPL
260
QDVYKIGGIG
270
TVPVGRVETG
280
VLKPGMVVTF
290
APVNVTTEVK
300
SVEMHHEALS
310
EALPGDNVGF
320
NVKNVSVKDV
330
RRGNVAGDSK
340
NDPPMEAAGF
350
TAQVIILNHP
360
GQISAGYAPV
370
LDCHTAHIAC
380
KFAELKEKID
390
RRSGKKLEDG
400
PKFLKSGDAA
410
IVDMVPGKPM
420
CVESFSDYPP
430
LGRFAVRDMR
440
QTVAVGVIKA
450
VDKKAAGAGK
460
VTKSAQKAQK
AK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030864 | cortical actin cytoskeleton |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0032587 | ruffle membrane |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0019209 | kinase activator activity |
| Molecular Function | GO:0060090 | molecular adaptor activity |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0003746 | translation elongation factor activity |
| Molecular Function | GO:0000049 | tRNA binding |
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:0044829 | host-mediated activation of viral genome replication |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.