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Overview

Uniprot IDH0V2J1
Protein NameHeat shock cognate 71 kDa protein
Gene NameHspa8
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
500 KSTGKENKITITNDK
507 KITITNDKGRLSKED
512 NDKGRLSKEDIERMV
601 HQQKELEKVCNPIIT

Function

No function data available.

Protein Sequence

10 MSKGPAVGID 20 LGTTYSCVGV 30 FQHGKVEIIA 40 NDQGNRTTPS 50 YVAFTDTERL 60 IGDAAKNQVA 70 MNPTNTVFDA 80 KRLIGRRFDD 90 AVVQSDMKHW 100 PFMVVNDAGR 110 PKVQVEYKGE 120 TKSFYPEEVS 130 SMVLTKMKEI 140 AEAYLGKTVT 150 NAVVTVPAYF 160 NDSQRQATKD 170 AGTIAGLNVL 180 RIINEPTAAA 190 IAYGLDKKVG 200 AERNVLIFDL 210 GGGTFDVSIL 220 TIEDGIFEVK 230 STAGDTHLGG 240 EDFDNRMVNH 250 FIAEFKRKHK 260 KDISENKRAV 270 RRLRTACERA 280 KRTLSSSTQA 290 SIEIDSLYEG 300 IDFYTSITRA 310 RFEELNADLF 320 RGTLDPVEKA 330 LRDAKLDKSQ 340 IHDIVLVGGS 350 TRIPKIQKLL 360 QDFFNGKELN 370 KSINPDEAVA 380 YGAAVQAAIL 390 SGDKSENVQD 400 LLLLDVTPLS 410 LGIETAGGVM 420 TVLIKRNTTI 430 PTKQTQTFTT 440 YSDNQPGVLI 450 QVYEGERAMT 460 KDNNLLGKFE 470 LTGIPPAPRG 480 VPQIEVTFDI 490 DANGILNVSA 500 VDKSTGKENK 510 ITITNDKGRL 520 SKEDIERMVQ 530 EAEKYKAEDE 540 KQRDKVSSKN 550 SLESYAFNMK 560 ATVEDEKLQG 570 KINDEDKQKI 580 LDKCNEIINW 590 LDKNQTAEKE 600 EFEHQQKELE 610 KVCNPIITKL 620 YQSAGGMPGG 630 MPGGFPGGGA 640 PPSGGASSGP TIEEVD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0098690 glycinergic synapse
Cellular Component GO:0005765 lysosomal membrane
Cellular Component GO:0042470 melanosome
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0101031 protein folding chaperone complex
Cellular Component GO:0000974 Prp19 complex
Cellular Component GO:0005681 spliceosomal complex
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0140545 ATP-dependent protein disaggregase activity
Molecular Function GO:0055131 C3HC4-type RING finger domain binding
Molecular Function GO:0001664 G protein-coupled receptor binding
Molecular Function GO:0031072 heat shock protein binding
Molecular Function GO:0051087 protein-folding chaperone binding
Molecular Function GO:0030674 protein-macromolecule adaptor activity
Molecular Function GO:0048018 receptor ligand activity
Molecular Function GO:0031625 ubiquitin protein ligase binding
Molecular Function GO:0051082 unfolded protein binding
Biological Process GO:0046034 ATP metabolic process
Biological Process GO:0072318 clathrin coat disassembly
Biological Process GO:0006397 mRNA processing
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:1900226 negative regulation of NLRP3 inflammasome complex assembly
Biological Process GO:1902904 negative regulation of supramolecular fiber organization
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0160020 positive regulation of ferroptosis
Biological Process GO:0042026 protein refolding
Biological Process GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0008380 RNA splicing

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.