Search Results
Overview
| Uniprot ID | H0V391 |
|---|---|
| Protein Name | U5 small nuclear ribonucleoprotein 40 kDa protein |
| Gene Name | SNRNP40 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 18 | ELPLVPVKRQRHELQ |
| 271 | DVRPFAPKERCVKIF |
| 8 | MIEQAKRKAPELPLV |
Function
Required for pre-mRNA splicing as component of the activated spliceosome. Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs
Protein Sequence
10
MIEQAKRKAP
20
ELPLVPVKRQ
30
RHELQLAAAG
40
SGPGTGQQQA
50
APGALLQAGP
60
PRCSSLQAPI
70
MLLSGHEGEV
80
YCCKFHPNGS
90
TLASAGFDRL
100
ILLWNVYGDC
110
DNYATLKGHS
120
GAVMELHYNT
130
DGSMLFSAST
140
DKTVAVWDSE
150
TGERVKRLKG
160
HTSFVNSCYP
170
ARRGPQLVCT
180
GSDDGTVKLW
190
DIRKKAAIQT
200
FQNTYQVLAV
210
TFNDTSDQII
220
SGGIDNDIKV
230
WDLRQNKLTY
240
TMRGHADSVT
250
GLSLSSEGSY
260
LLSNAMDNTV
270
RVWDVRPFAP
280
KERCVKIFQG
290
NVHNFEKNLL
300
RCSWSPDGSK
310
IAAGSADRFV
320
YVWDTTSRRI
330
LYKLPGHAGS
340
INEVAFHPDE
350
PIILSASSDK
RLYMGEIQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Cellular Component | GO:0005682 | U5 snRNP |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0000375 | RNA splicing, via transesterification reactions |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.