Search Results

Overview

Uniprot IDH0V4L0
Protein NameAP-3 complex subunit mu-1
Gene NameAP3M1
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
398 RLDMYGEKYKPFKGV

Function

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes

Protein Sequence

10 MIHSLFLINC 20 SGDIFLEKHW 30 KSVVSQSVCD 40 YFFEAQEKAA 50 DVENVPPVIS 60 TPHHYLISIY 70 RDKLFFVSVI 80 QTEVPPLFVI 90 EFLHRVADTF 100 QDYFGECSEA 110 AIKDNVVIVY 120 ELLEEMLDNG 130 FPLATESNIL 140 KELIKPPTIL 150 RSVVNSITGS 160 SNVGDTLPTG 170 QLSNIPWRRA 180 GVKYTNNEAY 190 FDVVEEIDAI 200 IDKSGSTVFA 210 EIQGVIDACI 220 KLSGMPDLSL 230 SFMNPRLLDD 240 VSFHPCIRFK 250 RWESERVLSF 260 IPPDGNFRLI 270 SYRVSSQNLV 280 AIPVYVKHSI 290 SFKENSSCGR 300 FDITIGPKQN 310 MGKTIEGITV 320 TVHMPKVVLN 330 MNLTPTQGSY 340 TFDPVTKILT 350 WDVGKITPQK 360 LPSLKGLVNL 370 QSGAPKPEEN 380 PSLNIQFKIQ 390 QLAISGLKVN 400 RLDMYGEKYK 410 PFKGVKYVTK AGKFQVRT

Gene Ontology

Classification GO ID Description
Cellular Component GO:1904115 axon cytoplasm
Cellular Component GO:0030131 clathrin adaptor complex
Cellular Component GO:0030659 cytoplasmic vesicle membrane
Cellular Component GO:0005794 Golgi apparatus
Cellular Component GO:0098837 postsynaptic recycling endosome
Molecular Function GO:0031267 small GTPase binding
Biological Process GO:0048490 anterograde synaptic vesicle transport
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0098884 postsynaptic neurotransmitter receptor internalization

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.