Search Results
Overview
| Uniprot ID | H0V7D0 |
|---|---|
| Protein Name | Spliceosome-associated protein CWC15 homolog |
| Gene Name | CWC15 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 18 | PARGGRGKGEGDLSQ |
| 28 | GDLSQLSKQYSSRDL |
| 40 | RDLPSHTKIKYRQTT |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs
Protein Sequence
10
MTTAARPTFE
20
PARGGRGKGE
30
GDLSQLSKQY
40
SSRDLPSHTK
50
IKYRQTTQDA
60
PEEVRNRDFR
70
RELEERERAA
80
AREKNRDRPT
90
REHTTSSSVS
100
KKPRLDQIPA
110
ANLDADDPLT
120
DEEDEDFEEE
130
SDDDDTAALL
140
AELEKIKKER
150
AEEQARKEQE
160
QKAEEERIRM
170
ENILSGNPLL
180
NLTGPSQPQA
190
NFKVKRRWDD
200
DVVFKNCAKG
210
VDDQKKDKRF
220
VNDTLRSEFH
KKFMEKYIK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0045292 | mRNA cis splicing, via spliceosome |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.