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Overview

Uniprot IDH0V831
Protein NameThymocyte nuclear protein 1
Gene NameTHYN1
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
16 AGTSGPDKKGLSGKR

Function

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC

Protein Sequence

10 MPRPWKRLAG 20 TSGPDKKGLS 30 GKRTKTENSN 40 ELSALVENSN 50 AQTTSDSKNH 60 GQNLSNYWLM 70 KTEPESRLEK 80 GVDVKFSIED 90 LKAEPEQTAC 100 WDGVRNYQAR 110 NFLRAMKLED 120 EAFFYHSNCK 130 EPGIAGLVKI 140 VKEAYPDHTQ 150 FEKNSPHYDP 160 SSKKDNPKWF 170 MVDVQLVRKL 180 KRFISLAELK 190 TYHQAHKTSD 200 GPLKNMALFT 210 RQRLSIQSLT 220 QEEFDFILHL EEKEAN

Gene Ontology

Classification GO ID Description
Cellular Component GO:0001650 fibrillar center
Cellular Component GO:0005654 nucleoplasm

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.