Search Results
Overview
| Uniprot ID | H0V8S4 |
|---|---|
| Protein Name | Calponin |
| Gene Name | CNN3 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 191 | TNKVASQKGMSVYGL |
| 91 | TRRFDEGKLKAGQSV |
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Protein Sequence
10
IASKYDHQAE
20
EDLRNWIEEV
30
TGMSIGTNFQ
40
LGLKDGIILC
50
ELINKLQPGS
60
VKKVNESSLN
70
WPQAKTKGFH
80
TTIDIGVKYA
90
EKQTRRFDEG
100
KLKAGQSVIG
110
LQMGTNKCAS
120
QAGMTAYGTR
130
RHLYDPKMQT
140
DKPFDQTTIS
150
LQMGTNKGAS
160
QAGMLAPGTR
170
RDIYDQKLTL
180
QPVDNSTISL
190
QMGTNKVASQ
200
KGMSVYGLGR
210
QVYDPKYCAA
220
PTEPVIHNGS
230
QGTGTNGSEI
240
SDSDYQAEYP
250
DEYHGEYQDD
260
YPRDYQYGDQ
GIDY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005925 | focal adhesion |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0031032 | actomyosin structure organization |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.