Search Results
Overview
| Uniprot ID | H0VD76 |
|---|---|
| Protein Name | Ribosome biogenesis protein WDR12 |
| Gene Name | WDR12 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 239 | NRPRKKQKTEQLGLT |
Function
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome
Protein Sequence
10
MAQLQTRFFT
20
DNKKYAVDDV
30
PFSIPASSEI
40
ADLSNIINKL
50
LEAKNEFHKY
60
VEFDFLIKGQ
70
FLRMPLAKHM
80
EVENISSEEV
90
VELEYVEKYT
100
APQPEQCMFH
110
DDWVSAVKGA
120
EEWILTGSYD
130
KTSRIWSLEG
140
TSIMTIVGHT
150
DVVKDVAWVK
160
KDSLSCLLLS
170
ASMDQTILLW
180
EWSVERNKVK
190
ALHCCRGHAG
200
SVDSIAVDSS
210
GTKFCSGSWD
220
KMLKIWSAVP
230
TDEEDEMEES
240
TNRPRKKQKT
250
EQLGLTRTPI
260
VTLSGHTEAI
270
SSVLWSDAEE
280
ICSASWDHTI
290
RVWDVESGSL
300
KSTLTGNKVF
310
NCISYSPLCK
320
RLASGSTDRH
330
IRLWDPRTKD
340
GSLVSLSLTS
350
HTGWVTSVKW
360
SPTHEQQLIS
370
GSLDNIVKLW
380
DTRSCKAPLY
390
DLAAHEDKVL
400
SVDWTDTGLL
410
LSGGADNKLY
420
SYRYSPTTSH
VGA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0070545 | PeBoW complex |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Molecular Function | GO:0043021 | ribonucleoprotein complex binding |
| Biological Process | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0051726 | regulation of cell cycle |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.