Search Results

Overview

Uniprot IDH0VE35
Protein NameADP/ATP translocase
Gene NameSLC25A5
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
105 IFLGGVDKRTQFWRY
147 RLAADVGKAGAEREF
155 AGAEREFKGLGDCLV
163 GLGDCLVKIYKSDGI
166 DCLVKIYKSDGIKGL
23 GVAAAISKTAVAPIE
33 VAPIERVKLLLQVQH
63 DCVVRIPKEQGVLSF
92 QALNFAFKDKYKQIF
96 FAFKDKYKQIFLGGV

Function

Catalyzes the exchange of ADP and ATP across the membrane

Protein Sequence

10 MTDAAVSFAK 20 DFLAGGVAAA 30 ISKTAVAPIE 40 RVKLLLQVQH 50 ASKQITADKQ 60 YKGIIDCVVR 70 IPKEQGVLSF 80 WRGNLANVIR 90 YFPTQALNFA 100 FKDKYKQIFL 110 GGVDKRTQFW 120 RYFAGNLASG 130 GAAGATSLCF 140 VYPLDFARTR 150 LAADVGKAGA 160 EREFKGLGDC 170 LVKIYKSDGI 180 KGLYQGFNVS 190 VQGIIIYRAA 200 YFGIYDTAKG 210 MLPDPKNTHI 220 IVSWMIAQTV 230 TAVAGLTSYP 240 FDTVRRRMMM 250 QSGRKGTDIM 260 YTGTLDCWRK 270 IARDEGGKAF 280 FKGAWSNVLR 290 GMGGAFVLVL YDEIKKFT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0042645 mitochondrial nucleoid
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Cellular Component GO:0071817 MMXD complex
Molecular Function GO:0005471 ATP:ADP antiporter activity
Molecular Function GO:0017077 oxidative phosphorylation uncoupler activity
Molecular Function GO:0015078 proton transmembrane transporter activity
Molecular Function GO:0031625 ubiquitin protein ligase binding
Biological Process GO:1990845 adaptive thermogenesis
Biological Process GO:0030183 B cell differentiation
Biological Process GO:0007059 chromosome segregation
Biological Process GO:0030218 erythrocyte differentiation
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:1901526 positive regulation of mitophagy

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.