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Overview

Uniprot ID	H0VE99
Protein Name	Pre-mRNA-splicing factor SYF1
Gene Name	XAB2
Organism	Cavia porcellus

Kla Sites from experimental identification

Position	Flanking peptide
794	QPSRAQSKILFVRSD

Function

Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing

Protein Sequence

10 MVVMARLSRA 20 ERPDLVFEEE 30 DLPYEEEIMR 40 NQFSVKCWLR 50 YIEFKQGAPK 60 PRLNQLYERA 70 LKLLPCSYKL 80 WYRYLKARRA 90 QVKHRCVTDP 100 AYEDVNNCHE 110 RAFVFMHKMP 120 RLWLDYCQFL 130 MDQGRVTHTR 140 RTFDRALRAL 150 PITQHSRIWP 160 LYLRFLRSHP 170 LPETAVRGYR 180 RFLKLSPESA 190 EEYIEYLKSS 200 DRLDEAAQRL 210 ATVVNDERFV 220 SKAGKSNYQL 230 WHELCDLISQ 240 NPDKVQSLNV 250 DAIIRGGLTR 260 FTDQLGKLWC 270 SLADYYIRSG 280 HFEKARDVYE 290 EAIRTVMTVR 300 DFTQVFDSYA 310 QFEERMIAAK 320 METTSELGRE 330 EEDDVDLELR 340 LARFEQLISR 350 RPLLLNSVLL 360 RQNPHHVHEW 370 HKRVALHQGR 380 PREIINTYTE 390 AVQTVDPFKA 400 TGKPHTLWVA 410 FAKFYEDNGQ 420 LDDARVILEK 430 ATKVNFKQVD 440 DLASVWCQCG 450 ELELRHENYD 460 EALRLLRKAT 470 ALPARRAEYF 480 DGSEPVQNRV 490 YKSLKVWSML 500 ADLEESLGTF 510 QSTKAVYDRI 520 LDLRIATPQI 530 IINYAMFLEE 540 HKYFEESFKA 550 YERGISLFKW 560 PNVSDIWSTY 570 LTKFIARYGG 580 RKLERARDLF 590 EQALDGCPPK 600 YAKTLYLLYA 610 QLEEEWGLAR 620 HAMAVYDRAT 630 RAVEPTQQYD 640 MFNIYIKRAA 650 EIYGVTHTRG 660 IYQKAIEVLS 670 DEHAREMCLR 680 FADMECKLGE 690 IDRARAIYSF 700 CSQICDPRTT 710 SAFWQTWKHF 720 EVQHGNEDTI 730 REMLRIRRSV 740 QATYNTQVNF 750 MASQMLKVSG 760 SATGTVSDLA 770 PGQSGMDDMK 780 LLEQRAEQLA 790 AEAERDQPSR 800 AQSKILFVRS 810 DASREELAEL 820 AQQANPDEIQ 830 LGEDEDEDEM 840 DLEPNEVRLE 850 QQSVPAAVFG SLKED

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0071014	post-mRNA release spliceosomal complex
Cellular Component	GO:0000974	Prp19 complex
Cellular Component	GO:0071007	U2-type catalytic step 2 spliceosome
Biological Process	GO:0006351	DNA-templated transcription
Biological Process	GO:0000349	generation of catalytic spliceosome for first transesterification step
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.