Search Results
Overview
| Uniprot ID | H0VEG1 |
|---|---|
| Protein Name | Protein phosphatase 1 regulatory subunit 14 |
| Gene Name | PPP1R14A |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | LGKRVLNKLQSPSRA |
Function
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction
Protein Sequence
10
MAAQRLGKRV
20
LNKLQSPSRA
30
RGPGGSPGGL
40
QKRHARVTVK
50
YDRRELQRRL
60
DVEKWIDGRL
70
EELYRGREAD
80
MPDEVNIDEL
90
LELESEEDRT
100
RKIQGLLTSC
110
TNPTEDFVQE
120
LLDQAWTAPP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0004865 | protein serine/threonine phosphatase inhibitor activity |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.