Search Results
Overview
| Uniprot ID | H0VF39 |
|---|---|
| Protein Name | General transcription factor IIE subunit 1 |
| Gene Name | GTF2E1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 330 | RALLIHEKKTPTAAA |
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase
Protein Sequence
10
MADPDVLTEV
20
PAALKRLAKY
30
VIRGFYGIEH
40
VLALDILIRN
50
PCVKEEDMLE
60
LLKFDRKQLR
70
SVLNNLKGDK
80
FIKCRMRVET
90
AADGKTTRHN
100
YYFINYRTLV
110
NVVKYKLDHM
120
RRRIETDERD
130
STNRASFKCP
140
VCCSTFTDLE
150
ANQLFDPMTG
160
TFRCTFCHTE
170
VEEDESAMPK
180
KDARTLLARF
190
NEQIEPIYAL
200
LRETEDVNLA
210
YEVLEPEPTE
220
ISALKQSKDR
230
AASTAGAAGQ
240
AGGHHREAWA
250
TRGPSYEDLY
260
TQNVVINMDD
270
QEDVHRASLE
280
GKSAKERPIW
290
LRESTVQGSY
300
SSEEMKEGGL
310
DMDAFQEREE
320
GHTGPDDNEE
330
VMRALLIHEK
340
KTPTAAASSV
350
GAAAPVAATN
360
PSDSESETSE
370
SDDDSPPRPA
380
VTVAMHRREE
390
DEEDEEEFEE
400
VADDPVVMVA
410
GHPFSYSEVS
420
QRPELVAQMT
430
PEEKEAYIAM
440
GQRMFQDLFE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005669 | transcription factor TFIID complex |
| Cellular Component | GO:0005673 | transcription factor TFIIE complex |
| Molecular Function | GO:0016251 | RNA polymerase II general transcription initiation factor activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0051123 | RNA polymerase II preinitiation complex assembly |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.