Search Results

Overview

Uniprot IDH0VHG7
Protein NameTranscriptional repressor CTCF
Gene NameCTCF
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
192 PDYQPPAKKTKKPKR

Function

No function data available.

Protein Sequence

10 MEGEAVEAIV 20 EESETFIKGK 30 ERKTYQRRRE 40 GGQEEDACHL 50 PQNQTDGGEV 60 VQDVNSSVQM 70 VMMEQLDPTL 80 LQMKTEVMEG 90 SVAPEAEAAV 100 DDTQIITLQV 110 VNMEEQPINI 120 GELQLVQVPV 130 PVTVPVATTS 140 VEELQGAYEN 150 EVSKEGLAES 160 EPMICHTLPL 170 PEGFQVTLEQ 180 GALPPQKILA 190 GKKDPDYQPP 200 AKKTKKPKRE 210 GKDVDVSVYD 220 FEEEQQEGLL 230 SEVNAEKVVG 240 NMKPPKPTKI 250 KKKGVKKTFQ 260 CELCSYTCPR 270 RSNLDRHMKS 280 HTDERPHKCH 290 LCGRAFRTVT 300 LLRNHLNTHT 310 GTRPHKCPDC 320 DMAFVTSGEL 330 VRHRRYKHTH 340 EKPFKCSMCD 350 YASVEVSKLK 360 RHIRSHTGER 370 PFQCSLCSYA 380 SRDTYKLKRH 390 MRTHSGEKPY 400 ECYICHARFT 410 QSGTMKMHIL 420 QKHTENVAKF 430 HCPHCDTVIA 440 RKSDLGVHLR 450 KQHSYIEQGK 460 KCRYCDAVFH 470 ERYALIQHQK 480 SHKNEKRFKC 490 DQCDYACRQE 500 RHMIMHKRTH 510 TGEKPYACSH 520 CDKTFRQKQL 530 LDMHFKRYHD 540 PNFVPAAFVC 550 SKCGKTFTRR 560 NTMARHADNC 570 AGPDGVEGEN 580 GGETKKSKRG 590 RKRKMRSKKE 600 DSSDSEENAE 610 PDLDDNEDEE 620 EPAVEIEPEP 630 EPQPVTPAPP 640 PAKKRRGRPP 650 GRTNQPKQNQ 660 PTAIIQVEDQ 670 NTGAIENIIV 680 EVKKEPDAEP 690 VEGEEEEAQP 700 ATTDAPNGDL 710 TPEMILSMMD R

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000775 chromosome, centromeric region
Cellular Component GO:0000793 condensed chromosome
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0043035 chromatin insulator sequence binding
Molecular Function GO:0140587 chromatin loop anchoring activity
Molecular Function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0001221 transcription coregulator binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0140588 chromatin looping
Biological Process GO:0007059 chromosome segregation
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0071514 genomic imprinting
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0071459 protein localization to chromosome, centromeric region

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.