Search Results
Overview
| Uniprot ID | H0VI33 |
|---|---|
| Protein Name | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit |
| Gene Name | PPP2R5D |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 564 | EKVLLRRKSELPQDV |
| 65 | PTQLSKIKYSGGPQI |
| 74 | SGGPQIVKKERRQSS |
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment
Protein Sequence
10
MPYKLKKEKE
20
TPKLAKGTTK
30
PSSSGKDGGG
40
DSAEEAQPQP
50
QPQAPPSNKR
60
PSNSTPPPTQ
70
LSKIKYSGGP
80
QIVKKERRQS
90
SSRFNLSKNR
100
ELQKLPALKD
110
SPTQEREELF
120
IQKLRQCCVL
130
FDFVSDPLSD
140
LKFKEVKRAG
150
LNEMVEYITH
160
SRDVVTEAIY
170
PEAVTMFSVN
180
LFRTLPPSSN
190
PTGAEFDPEE
200
DEPTLEAAWP
210
HLQLVYEFFL
220
RFLESPDFQP
230
NIAKKYIDQK
240
FVLALLDLFD
250
SEDPRERDFL
260
KTILHRIYGK
270
FLGLRAYIRR
280
QINHIFYRFI
290
YETEHHNGIA
300
ELLEILGSII
310
NGFALPLKEE
320
HKMFLIRVLL
330
PLHKVKSLSV
340
YHPQLAYCVV
350
QFLEKESSLT
360
EPVIVGLLKF
370
WPKTHSPKEV
380
MFLNELEEIL
390
DVIEPSEFSK
400
VMEPLFRQLA
410
KCVSSPHFQV
420
AERALYYWNN
430
EYIMSLISDN
440
AARVLPIMFP
450
ALYRNSKSHW
460
NKTIHGLIYN
470
ALKLFMEMNQ
480
KLFDDCTQQY
490
KAEKQKGRFR
500
MKEREEMWQK
510
IEELARLNPQ
520
YPMFRAPPPL
530
PPVYSMETET
540
PTAEDIQLLK
550
RTVETEAVQM
560
LKDIKKEKVL
570
LRRKSELPQD
580
VYTIKALEAH
590
KRAEEFLTAS
QEAL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0000159 | protein phosphatase type 2A complex |
| Molecular Function | GO:0072542 | protein phosphatase activator activity |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.