Search Results
Overview
| Uniprot ID | H0VJK8 |
|---|---|
| Protein Name | Dynein light intermediate chain |
| Gene Name | DYNC1LI1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 385 | KLQSLLAKQPPTAAG |
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes
Protein Sequence
10
MAAVGRVGSF
20
GSSPPGLAST
30
YAGGPLANEL
40
ASGNGGAAAG
50
DEEDGQNLWS
60
CILSEVSTRS
70
RSKLPAGKNV
80
LLLGEDGAGK
90
TSLIRKIQGI
100
EEYKKGRGLE
110
YLYLNVHDED
120
RDDQTRCNVW
130
ILDGDLYHKG
140
LLKFSLDAVS
150
LKDTLVMLVV
160
DMSKPWTALD
170
SLQKWASVVR
180
EHVDKLKIPP
190
EEMKEMEQKL
200
IRDFQEYVEP
210
GEEFPASPQR
220
RGTTSQEDKD
230
DSVVLPLGAD
240
TLTHNLGIPI
250
LVVCTKCDAI
260
SVLEKEHDYR
270
DEHFDFIQSH
280
IRKFCLQYGA
290
ALIYTSVKEN
300
KNIDLVYKYI
310
VQKLYGFPYK
320
IPAVVVEKDA
330
VFIPAGWDND
340
KKIGILHENF
350
QTLKAEDNFE
360
DIITKPPVRK
370
FVHEKEIMAE
380
DDQVFLMKLQ
390
SLLAKQPPTA
400
AGRPVDASPR
410
VPGGSPQTPN
420
RSVSSNVASV
430
SPIPAGSKKI
440
DPNMKAGATS
450
EGVLANFFNS
460
LLSKKTGSPG
470
GPGVSGGSPG
480
VGAGGGSSGL
490
PPSAKKSGQK
500
PVLSDVHAEL
510
DRITRKPVSV
520
SPTTPTSPTE
GEAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005868 | cytoplasmic dynein complex |
| Cellular Component | GO:0030666 | endocytic vesicle membrane |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0000922 | spindle pole |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0045504 | dynein heavy chain binding |
| Molecular Function | GO:0019003 | GDP binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0061502 | early endosome to recycling endosome transport |
| Biological Process | GO:0000226 | microtubule cytoskeleton organization |
| Biological Process | GO:0007018 | microtubule-based movement |
| Biological Process | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint |
| Biological Process | GO:0060627 | regulation of vesicle-mediated transport |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.